X-Men: Apocalypse is a 2016 American superhero film based on the fictional X-Men characters that appear in Marvel Comics. It is the ninth installment in the X-Men film series and a sequel to 2014’s X-Men: Days of Future Past. Directed by Bryan Singer, with a screenplay by Simon Kinberg from a story conceived by Singer, Kinberg, Michael Dougherty and Dan Harris, the film stars an ensemble cast, led by James McAvoy, Michael Fassbender, Jennifer Lawrence, Oscar Isaac, Nicholas Hoult, Rose Byrne, Tye Sheridan, Sophie Turner, Olivia Munn and Lucas Till. In X-Men: Apocalypse, the ancient mutant En Sabah Nur awakens in 1983 and plans to cleanse the human race and take over the world, leading the X-Men to try to stop him and defeat his team of renegade mutants.
En Sabah Nur, a powerful mutant believed to be the first of his kind, rules ancient Egypt until he is betrayed by his worshippers, who entomb him alive. His four lieutenants die preserving him. Awakening in 1983, he believes humanity has lost its way without his presence. Aiming to destroy the world and remake it, he recruits Cairo pickpocket Ororo Munroe, who can control weather, and upgrades her power.
In East Berlin, shape-shifting mutant Raven investigates an underground fight club and discovers mutant champion Angel, who possesses a pair of large feathered wings on his back, and Kurt Wagner, who can teleport. Raven rescues Kurt and employs the services of black marketeer Caliban to transport him to America. En Sabah Nur recruits Caliban’s enforcer, Psylocke, who leads him to Angel. En Sabah Nur enhances both their powers, transforming Angel’s wings into metal.
Alex Summers discovers that his younger brother, Scott, is manifesting his mutation for shooting optic beams. Alex takes Scott to Professor Charles Xavier’s educational institute in Westchester County, New York in hopes that Xavier and Hank McCoy will teach him how to control his abilities. Scott meets the telepathic and telekinetic Jean Grey, and the two develop an attraction. Raven brings Kurt to the institute. Apocalypse’s powers cause disturbances around the world, leading Xavier and Alex to consult with CIA agent Moira MacTaggert, who has been researching the legend of Nur.
In Poland, the metal-controlling mutant Erik Lehnsherr lives with his wife and their young daughter, Nina. He uses his powers to save a coworker, prompting police to come capture him. When they accidentally kill Erik’s family, he retaliates by murdering them. En Sabah Nur approaches the disheartened Erik in Erik’s factory, kills Erik’s co-workers and takes him to Auschwitz, where Erik’s power first manifested. Erik destroys the camp and joins him.
En Sabah Nur enters Xavier’s mind while Xavier is using the mutant-locating computer Cerebro and, co-opting Xavier’s powers, forces all global superpowers to launch Earth’s entire nuclear arsenal into space to prevent interference. He and his new lieutenants arrive at the mansion and kidnap Xavier. Attempting to stop them, Alex accidentally causes an explosion that destroys the mansion. Peter Maximoff — having learned that he is Erik’s son, and hoping that Xavier can help to find him —– arrives in time to use his superspeed to evacuate the students just before the explosion destroys the building, but Alex is presumed dead. Colonel William Stryker’s forces subsequently capture Hank, Raven, Peter, and Moira, and take them to a military facility for interrogation. Scott, Jean and Kurt covertly follow and liberate their comrades using Stryker’s mind-controlled and brainwashed experiment, Weapon X, whose memories Jean partially restores.
At En Sabah Nur’s behest, Erik uses his powers to control Earth’s magnetic poles, causing widespread destruction across the planet and mass casualties. En Sabah Nur plans to transfer his consciousness into Xavier’s body and use Xavier’s power to enslave the minds of every person on earth. Xavier secretly sends a telepathic distress call to Jean, and the others travel to Cairo to battle Apocalypse and his horsemen. They rescue Xavier, but he loses his hair as the process nears completion. Angel is defeated and killed in the battle. Erik and Ororo are convinced to turn on En Sabah Nur and, with the help of Cyclops, they keep him occupied physically while Xavier fights him telepathically in the astral plane. Finally, Xavier encourages Jean to unleash the full extent of her powers, incinerating En Sabah Nur. In the ensuing chaos, Psylocke flees.
Xavier restores Moria’s memories, and they rekindle their relationship. Erik and Jean help reconstruct the school, but Erik refuses Xavier’s offer to stay and help teach. Peter decides not to tell Erik yet that he is his son. As the new X-Men, Hank and Raven train new recruits Scott, Jean, Ororo, Kurt and Peter.
In a post-credits scene, men in suits visit the Weapon X facility to retrieve data on Stryker’s mutant research, including an X-ray and a blood sample marked “Weapon X”, on behalf of the Essex Corporation.